Anti-TSG6/TNFAIP6 Antibody Picoband®

SKU: A03433-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Rat

Applications: WB

Application Details: Western blot, 0.1-0.5μg/ml, Human, Rat

Gene Name: TNFAIP6

Specificity: No cross reactivity with other proteins.

Background: Tumor necrosis factor-inducible gene 6 protein, also known as TSG-6, is a protein that in humans is encoded by the TNFAIP6 gene. The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TSG6, different from the related mouse sequence by two amino acids.

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: TNFAIP6 tumor necrosis factor, alpha-induced protein 6. 2. Lee TH, Klampfer L, Shows TB, Vilcek J (March 1993). Transcriptional regulation of TSG6, a tumor necrosis factor- and interleukin-1-inducible primary response gene coding for a secreted hyaluronan-binding protein. J. Biol. Chem. 268 (9): 6154–60. 3. Milner CM, Day AJ (2004). TSG-6: a multifunctional protein associated with inflammation.. J. Cell. Sci. 116 (Pt 10): 1863–73.

Uniprot ID: P98066

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 31 kDa.

Calculated Molecular Weight: 31203 MW

Gene ID: 7130

Protein Name: Tumor necrosis factor-inducible gene 6 protein

Gene Full Name: TNF alpha induced protein 6

Synonyms: Hyaluronate binding protein; TNF alpha induced protein 6; TNF stimulated gene 6 protein; TNFAIP6; TSG 6; TSG6; TSG-6