Anti-TRIR Antibody Picoband®

SKU: A32362

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human

Gene Name: TRIR

Specificity:

Background: Enables 3'-5' exonuclease activity and 5'-3' exonuclease activity. Involved in RNA phosphodiester bond hydrolysis, exonucleolytic and rRNA catabolic process.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TRIR, identical to the related mouse sequences.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Xie, J. , Zhen, C. , Zhang, X. , Chen, H. , & Guan, W. . (2017). Identification of an rnase that preferentially cleaves a/g nucleotides. Scientific Reports, 7, 45207. 2. Huang, X. , Leduc, R. D. , Fornelli, L. , Schunter, A. J. , Bennett, R. L. , & Kelleher, N. L. , et al. (2019). Defining the nsd2 interactome: parp1 parylation reduces nsd2 histone methyltransferase activity and impedes chromatin binding. Journal of Biological Chemistry. 3. Kim, H. , Dejsuphong, D. , Adelmant, G. , Ceccaldi, R. , & D'Andrea, A. D. . (2014). Transcriptional repressor zbtb1 promotes chromatin remodeling and translesion dna synthesis. Molecular Cell, 54(1).

Uniprot ID: Q9BQ61

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 24 kDa

Calculated Molecular Weight: 14377 MW

Gene ID: 79002

Protein Name: Telomerase RNA component interacting RNase

Gene Full Name: telomerase RNA component interacting RNase

Synonyms: C19orf43; fSAP18