Anti-TOMM40 Antibody Picoband®

SKU: A03166-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: TOMM40

Specificity:

Background: Translocase of outer mitochondrial membrane 40 homolog (yeast), also known as TOMM40, is a protein which in humans is encoded by the TOMM40 gene. The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene.

Immunogen: E.coli-derived human TOMM40 recombinant protein (Position: N111-K315).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Freitas, E. M., Zhang, W. J., Lalonde, J.-P., Tay, G. K., Gaudieri, S., Ashworth, L. K., van Bockxmeer, F. M., Dawkins, R. L. Sequencing of 42kb of the APO E-C2 gene cluster reveals a new gene: PEREC1. DNA Seq. 9: 89-101, 1998. 2. Gabriel, K., Egan, B., Lithgow, T. Tom40, the import channel of the mitochondrial outer membrane, plays an active role in sorting imported proteins. EMBO J. 22: 2380-2386, 2003. 3. Humphries, A. D., Streimann, I. C., Stojanovski, D., Johnston, A. J., Yano, M., Hoogenraad, N. J., Ryan, M. T. Dissection of the mitochondrial import and assembly pathway for human Tom40. J. Biol. Chem. 280: 11535-11543, 2005.

Uniprot ID: O96008

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 38 kDa

Calculated Molecular Weight: 65411 MW

Gene ID: 10452

Protein Name: Mitochondrial import receptor subunit TOM40 homolog

Gene Full Name: translocase of outer mitochondrial membrane 40

Synonyms: C19orf1; D19S1177E; p38.5; PER EC1; PEREC1; Protein Haymaker; TOM40; TOMM40