Anti-TBX4 Antibody Picoband®

SKU: A06607-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC,IF,Flow Cytometry

Application Details: Western blot, 0.25-0.5μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human

Gene Name: TBX4

Specificity:

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TBX4, which shares 81.8% amino acid (aa) sequence identity with mouse TBX4.

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Agulnik, S. I., Garvey, N., Hancock, S., Ruvinsky, I., Chapman, D. L., Agulnik, I., Bollag, R., Papaioannou, V., Silver, L. M. Evolution of mouse T-box genes by tandem duplication and cluster dispersion. Genetics 144: 249-254, 1996. 2. Bollag, R. J., Siegfried, Z., Cebra-Thomas, J. A., Garvey, N., Davison, E. M., Silver, L. M. An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T locus. Nature Genet. 7: 383-389, 1994. 3. Bongers, E. M. F., Van Bokhoven, H., Van Thienen, M.-N., Kooyman, M. A. P., Van Beersum, S. E. C., Boetes, C., Knoers, N. V. A. M., Hamel, B. C. J. The small patella syndrome: description of five cases from three families and examination of possible allelism with familial patella aplasia-hypoplasia and nail-patella syndrome. (Letter) J. Med. Genet. 38: 209-213, 2001.

Uniprot ID: P57082

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 60 kDa

Calculated Molecular Weight: 104553 MW

Gene ID: 9496

Protein Name: T-box transcription factor TBX4

Gene Full Name: T-box transcription factor 4

Synonyms: TBX4; T-box transcription factor TBX4; T-box protein 4