Anti-TACI/TNFRSF13B Antibody

SKU: A02952-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: IHC

Application Details: Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml

Gene Name: TNFRSF13B

Specificity: No cross reactivity with other proteins.

Background: Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) is a protein that in humans is encoded by the TNFRSF13B gene. The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17.

Immunogen: E. coli-derived human TACI recombinant protein (Position: M1-S165).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: TNFRSF13B tumor necrosis factor receptor superfamily, member 13B. 2. Seshasayee D, Valdez P, Yan M, Dixit VM, Tumas D, Grewal IS (February 2003). Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor. Immunity. 18 (2): 279–88.

Uniprot ID: O14836

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 40 kDa

Calculated Molecular Weight: 79686 MW

Gene ID: 23495

Protein Name: Tumor necrosis factor receptor superfamily member 13B

Gene Full Name: TNF receptor superfamily member 13B

Synonyms: TNF receptor superfamily member 13B; CD267; CVID; CVID2; IGAD2; RYZN; TACI; TNFRSF14B; TNFRSF13B