Anti-SRARP Antibody Picoband®

SKU: A31838-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: SRARP

Specificity:

Background: Enables nuclear estrogen receptor binding activity. Involved in positive regulation of intracellular estrogen receptor signaling pathway. Located in cytoplasm and nucleus.

Immunogen: E.coli-derived human SRARP recombinant protein (Position: K30-S147). Human SRARP shares 46.2% amino acid (aa) sequence identity with mouse SRARP.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Naderi, A. SRARP and HSPB7 are epigenetically regulated gene pairs that function as tumor suppressors and predict clinical outcome in malignancies. Molec. Oncol. 12: 724-755, 2018. 2. Su, D., Fu, X., Fan, S., Wu, X., Wang, X.-X., Fu, L., Dong, X.-Y., Ni, J. J., Fu, L., Zhu, Z., Dong, J.-T. Role of ERRF, a novel ER-related nuclear factor, in the growth control of ER-positive human breast cancer cells. Am. J. Path. 180: 1189-1201, 2012.

Uniprot ID: Q8NEQ6

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 18 kDa

Calculated Molecular Weight: 18 kDa

Gene ID: 149563

Protein Name: Steroid receptor-associated and regulated protein

Gene Full Name: steroid receptor associated and regulated protein

Synonyms: SRARP; C1orf64; ERRF; SSPR; Steroid receptor-associated and regulated protein; ER-related factor; Steroid receptor-regulated protein