Anti-SNX18 Antibody Picoband®

SKU: A09010-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SNX18

Specificity:

Background: Sorting nexin-18 is a protein that in humans is encoded by the SNX18 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human SNX18 recombinant protein (Position: R22-F628).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Håberg, K., Lundmark, R., & Carlsson, S. R. (2008). SNX18 is an SNX9 paralog that acts as a membrane tubulator in AP-1-positive endosomal trafficking. Journal of cell science, 121(9), 1495-1505. 2. Okano, M., Matsuo, H., Nishimura, Y., Hozumi, K., Yoshioka, S., Tonoki, A., & Itoh, M. (2016). Mib1 modulates dynamin 2 recruitment via Snx18 to promote Dll1 endocytosis for efficient Notch signaling. Genes to Cells, 21(5), 425-441. 3. Willenborg, C., Jing, J., Wu, C., Matern, H., Schaack, J., Burden, J., & Prekeris, R. (2011). Interaction between FIP5 and SNX18 regulates epithelial lumen formation. Journal of Cell Biology, 195(1), 71-86.

Uniprot ID: Q96RF0

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 69 kDa

Calculated Molecular Weight:

Gene ID: 112574

Protein Name: Sorting nexin-18

Gene Full Name: sorting nexin 18

Synonyms: SH3PX2; SH3PXD3B; SNAG1; SNX18; sorting nexin 18