Anti-Slc7a9 Antibody Picoband®

SKU: A03445-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: ELISA,Flow Cytometry,WB

Application Details: Western blot, 0.25-0.5μg/ml, Mouse, Rat
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Mouse
ELISA, 0.1-0.5μg/ml, -

Gene Name: Slc7a9

Specificity:

Background: b (0,+)-type amino acid transporter 1, also known as b (0,+)AT1, is a protein which in humans is encoded by the SLC7A9 gene. This gene encodes a protein that belongs to a family of light subunits of amino acid transporters. This protein plays a role in the high-affinity and sodium-independent transport of cystine and neutral and dibasic amino acids, and appears to function in the reabsorption of cystine in the kidney tubule. Mutations in this gene cause non-type I cystinuria, a disease that leads to cystine stones in the urinary system due to impaired transport of cystine and dibasic amino acids. Alternate transcript variants, which encode the same protein, have been found for this gene.

Immunogen: E.coli-derived mouse Slc7a9 recombinant protein (Position: M1-E487).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Brodehl, J., Gellissen, K., Kowalewski, S. Isolierter Defekt der tubulaeren Cystin-Rueckresorption in einer Familie mit idiopathischem Hypoparathyroidismus. Klin. Wschr. 45: 38-40, 1967. 2. Colombo, R. Dating the origin of the V170M mutation causing non-type I cystinuria in Libyan Jews by linkage disequilibrium and physical mapping of the SLC7A9 gene. Genomics 69: 131-134, 2000. 3. Dello Strologo, L., Pras, E., Pontesilli, C., Beccia, E., Ricci-Barbini, V., de Sanctis, L., Ponzone, A., Gallucci, M., Bisceglia, L., Zelante, L., Jimenez-Vidal, M., Font, M., Zorzano, A., Rousaud, F., Nunes, V., Gasparini, P., Palacin, M., Rizzoni, G. Comparison between SLC3A1 and SLC7A9 cystinuria patients and carriers: a need for a new classification. J. Am. Soc. Nephrol. 13: 2547-2553, 2002.

Uniprot ID: Q9QXA6

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 53 kDa

Calculated Molecular Weight: 31203 MW

Gene ID: 30962

Protein Name: b

Gene Full Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 9

Synonyms: Slc7a9; Bat1; Solute carrier family 7 member 9