Anti-SHC Monoclonal Antibody

SKU: M00796-1

Size: 100 μl

Storage: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Form: Liquid

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF,Flow Cytometry

Application Details: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
FC 1:50

Gene Name: SHC1

Specificity:

Background:

Immunogen: A synthesized peptide derived from human SHC Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals.

Clonality: Monoclonal

Contents: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Affinity-chromatography

Reconstitution:

Reference:

Uniprot ID: P29353

Host: Rabbit

Concentration: 0.5mg/ml

Conjugate:

Cross Reactivity:

Isotype: Rabbit IgG

Phospho_site:

Clone Number: Clone: ADFI-19

Observed Molecular Weight: 65-70 kDa

Calculated Molecular Weight: 42778 MW

Gene ID: 6464

Protein Name: SHC-transforming protein 1

Gene Full Name: SHC adaptor protein 1

Synonyms: SH2 domain protein C1; SHC; SHC transforming protein 1; SHC transforming protein 3; SHC transforming protein A; SHC1; SHCA