Anti-SCC112/PDS5A Antibody Picoband®

SKU: A06272-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: PDS5A

Specificity:

Background: Sister chromatid cohesion protein PDS5 homolog A is a protein that in humans is encoded by the PDS5A gene. The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human PDS5A recombinant protein (Position: M1-R1337).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Ishikawa, K., Nagase, T., Suyama, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 169-176, 1998. 2. Kumar, D., Sakabe, I., Patel, S., Zhang, Y., Ahmad, I., Gehan, E. A., Whiteside, T. L., Kasid, U. SCC-112, a novel cell cycle-regulated molecule, exhibits reduced expression in human renal carcinomas. Gene 328: 187-196, 2004. 3. Terret, M.-E., Sherwood, R., Rahman, S., Qin, J., Jallepalli, P. V. Cohesin acetylation speeds the replication fork. Nature 462: 231-234, 2009.

Uniprot ID: Q29RF7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 151 kDa

Calculated Molecular Weight: 49655 MW

Gene ID: 23244

Protein Name: Sister chromatid cohesion protein PDS5 homolog A

Gene Full Name: PDS5 cohesin associated factor A

Synonyms: KIAA0648, PDS5, PDS5A, PIG54, SCC 112, SCC112