Anti-S100A14 Antibody

SKU: A06301-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: IHC

Application Details: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human

Gene Name: S100A14

Specificity:

Background: S100 calcium binding protein A14 (S100A14) is a protein that in humans is encoded by the S100A14 gene. This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human S100A14, which shares 93.8% amino acid (aa) sequence identity with mouse S100A14.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Adam, P. J., Boyd, R., Tyson, K. L., Fletcher, G. C., Stamps, A., Hudson, L., Poyser, H. R., Redpath, N., Griffiths, M., Steers, G., Harris, A. L., Patel, S., Berry, J., Loader, J. A., Townsend, R. R., Daviet, L., Legrain, P., Parekh, R., Terrett, J. A. Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer. J. Biol. Chem. 278: 6482-6489, 2003. 2. Chen, H., Yu, D., Luo, A., Tan, W., Zhang, C., Zhao, D., Yang, M., Liu, J., Lin, D., Liu, Z. Functional role of S100A14 genetic variants and their association with esophageal squamous cell carcinoma. Cancer Res. 69: 3451-3457, 2009. 3. Pietas, A., Schluns, K., Marenholz, I., Schafer, B. W., Heizmann, C. W., Petersen, I. Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family. Genomics 79: 513-522, 2002.

Uniprot ID: Q9HCY8

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 18 kDa

Calculated Molecular Weight: 49655 MW

Gene ID: 57402

Protein Name: Protein S100-A14

Gene Full Name: S100 calcium binding protein A14

Synonyms: Protein S100 A14; S100A14; S100A15; S114