Anti-ROM1 Antibody Picoband®

SKU: A07035-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ROM1

Specificity:

Background: Rod outer segment membrane protein 1 is a protein that in humans is encoded by the ROM1 gene. This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa.

Immunogen: E.coli-derived human ROM1 recombinant protein (Position: G32-A337).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Bascom, R. A., Connell, G., Garcia-Heras, J., Collins, L., Ledbetter, D., Molday, R. S., Kalnins, V., McInnes, R. R. Molecular and ultrastructural characterization of the products of the human retinopathy candidate genes ROM1 and RDS. (Abstract) Am. J. Hum. Genet. 47 (suppl.): A101 only, 1990. 2. Bascom, R. A., Garcia-Heras, J., Hsieh, C.-L., Gerhard, D. S., Jones, C., Francke, U., Willard, H. F., Ledbetter, D. H., McInnes, R. R. Localization of the photoreceptor gene ROM1 to human chromosome 11 and mouse chromosome 19: sublocalization to human 11q13 between PGA and PYGM. Am. J. Hum. Genet. 51: 1028-1035, 1992. 3. Bascom, R. A., Liu, L., Chen, J., Duncan, A., Kimberling, W. J., Moller, C. G., Humphries, P., Nathans, J., McInnes, R. R. ROM1: a candidate gene for autosomal dominant retinitis pigmentosa (ADRP), Usher syndrome type 1, and Best vitelliform macular dystrophy. (Abstract) Am. J. Hum. Genet. 51 (suppl.): A6 only, 1992.

Uniprot ID: Q03395

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 37 kDa

Calculated Molecular Weight:

Gene ID: 6094

Protein Name: Rod outer segment membrane protein 1

Gene Full Name: retinal outer segment membrane protein 1

Synonyms: ROM; ROM1; ROSP1; Tetraspanin 23; Tspan 23; TSPAN23