Anti-REM2 Antibody Picoband®

SKU: A11219-2

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: REM2

Specificity:

Background: Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be involved in negative regulation of high voltage-gated calcium channel activity. Predicted to be active in plasma membrane.

Immunogen: E.coli-derived human REM2 recombinant protein (Position: R65-E257). Human REM2 shares 94.8% and 95.9% amino acid (aa) sequence identity with mouse and rat REM2, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Bierings, R., Beato, M., Edel, M. J. An endothelial cell genetic screen identifies the GTPase Rem2 as a suppressor of p19(ARF) expression that promotes endothelial cell proliferation and angiogenesis. J. Biol. Chem. 283: 4408-4416, 2008. 2. Edel, M. J., Menchon, C., Menendez, S., Consiglio, A., Raya, A., Belmonte, J. C. I. Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1. Genes Dev. 24: 561-573, 2010. 3. Finlin, B. S., Shao, H., Kadono-Okuda, K., Guo, N., Andres, D. A. Rem2, a new member of the Rem/Rad/Gem/Kir family of Ras-related GTPases. Biochem. J. 347: 223-231, 2000.

Uniprot ID: Q8IYK8

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 37 kDa

Calculated Molecular Weight: 37 kDa

Gene ID: 161253

Protein Name: GTP-binding protein REM 2

Gene Full Name: RRAD and GEM like GTPase 2

Synonyms: GTP binding protein REM 2; REM2