Anti-PTGR2 Antibody Picoband®

SKU: A10106-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: PTGR2

Specificity:

Background: This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants.

Immunogen: E.coli-derived human PTGR2 recombinant protein (Position: E26-Q305).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Yun-Chia, C. E. , Yi-Cheng, C. , Chia-Tung, S. , Yu-Wen, T. , Shu-Huei, T. , & Siow-Wey, H. , et al. (2016). Inhibition of prostaglandin reductase 2, a putative oncogene overexpressed in human pancreatic adenocarcinoma, induces oxidative stress-mediated cell death involving xct and cth gene expressions through 15-keto-pge2. Plos One, 11(1), e0147390. 2. Yun-Chia Chang, E. , Tsai, S. H. , Shun, C. T. , Hee, S. W. , Chang, Y. C. , & Tsai, Y. C. , et al. (2012). Prostaglandin reductase 2 modulates ros-mediated cell death and tumor transformation of gastric cancer cells and is associated with higher mortality in gastric cancer patients. American Journal of Pathology, 181(4), 1316-1326. 3. Gao, K. , Lockwood, W. , Li, J. , Lam, W. , & Li, G. . (2008). Genomic analyses identify gene candidates for acquired irinotecan resistance in melanoma cells. International Journal of Oncology, 32(6), 1343-1349.

Uniprot ID: Q8N8N7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 40 kDa

Calculated Molecular Weight: 41409 MW

Gene ID: 145482

Protein Name: Prostaglandin reductase 2

Gene Full Name: prostaglandin reductase 2

Synonyms: PGR2; PRG 2; prostaglandin reductase 2; PTGR2; ZADH1