Anti-Phospho-SMC1 (S957) Monoclonal Antibody

SKU: MP02148

Size: 100 μl

Storage: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Form: Liquid

Reactivity: Human

Applications: WB,IHC,ICC,IF

Application Details: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200

Gene Name: SMC1A

Specificity:

Background:

Immunogen: A synthesized peptide derived from human Phospho-SMC1 (S957) Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair . ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint. SMC1 phosphorylation is ATM-independent in cells subjected to other forms of DNA damage, including UV light and hydroxyurea treatment.

Clonality: Monoclonal

Contents: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Affinity-chromatography

Reconstitution:

Reference:

Uniprot ID: Q14683

Host: Rabbit

Concentration: 0.5mg/ml

Conjugate:

Cross Reactivity:

Isotype: Rabbit IgG

Phospho_site: S957

Clone Number: Clone: FCI-19

Observed Molecular Weight: 15 kDa

Calculated Molecular Weight: 26053 MW

Gene ID: 8243

Protein Name: Structural maintenance of chromosomes protein 1A

Gene Full Name: structural maintenance of chromosomes 1A

Synonyms: CDLS2; DXS423E; KIAA0178; SB1.8; SMC 1 alpha; SMC 1A; SMC protein 1A; SMC1; SMC1A; SMC1alpha; SMC1L1; SMCB