Anti-PFKP Antibody Picoband®

SKU: A07337-3

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: PFKP

Specificity:

Background: Phosphofructokinase, platelet, also known as PFKP is an enzyme which in humans is encoded by the PFKP gene. This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.

Immunogen: E.coli-derived human PFKP recombinant protein (Position: A55-V784). Human PFKP shares 90.1% and 89.8% amino acid (aa) sequence identity with mouse and rat PFKP, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Francke, U. Personal Communication. New Haven, Conn. 8/1983. 2. Gonzalez, G. H., Billerbeck, A. E. C., Takayama, L. C., Wajntal, A. Duplication 10p in a girl due to a maternal translocation t(10;14)(p11;q12). Am. J. Med. Genet. 14: 159-167, 1983. 3. Morrison, N., Simpson, C., Fothergill-Gilmore, L., Boyd, E., Connor, J. M. Regional chromosomal assignment of the human platelet phosphofructokinase gene to 10p15. Hum. Genet. 89: 105-106, 1992.

Uniprot ID: Q01813

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 86 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 5214

Protein Name: ATP-dependent 6-phosphofructokinase, platelet type

Gene Full Name: phosphofructokinase, platelet

Synonyms: 6 phosphofructokinase type C; PFK C; PFKF; PFKP; Phosphofructokinase 1; phosphofructokinase; platelet; Phosphohexokinase