Anti-PDC Antibody Picoband®

SKU: A00596-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
ELISA, 0.1-0.5 μg/ml

Gene Name: PDC

Specificity:

Background: This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen: E.coli-derived human PDC recombinant protein (Position: M1-E246). Human PDC shares 88.2% and 87.8% amino acid (aa) sequence identity with mouse and rat PDC, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Abe, T., Kikuchi, T., Shinohara, T. The sequence of the human phosducin gene (PDC) and its 5-prime-flanking region. Genomics 19: 369-372, 1994. 2. Craft, C. M., Lolley, R. N., Seldin, M. F., Lee, R. H. Rat pineal gland phosducin: cDNA isolation, nucleotide sequence, and chromosomal assignment in the mouse. Genomics 10: 400-409, 1991. 3. Ding, C., Li, X., Griffin, C. A., Jabs, E. W., Hawkins, A. L., Levine, M. A. The gene for human phosducin (PDC), a soluble protein that binds G-protein beta gamma dimers, maps to 1q25-q31.1. Genomics 18: 457-459, 1993.

Uniprot ID: P20941

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 28 kDa

Calculated Molecular Weight: 28 kDa

Gene ID: 5132

Protein Name: Phosducin

Gene Full Name: phosducin

Synonyms: PDC; Phosducin; PHD; 33 kDa phototransducing protein; Protein MEKA