Anti-ONECUT2 Antibody Picoband®

SKU: A09652-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse

Applications: WB

Application Details: Western blot, 0.1-0.5μg/ml

Gene Name: ONECUT2

Specificity: No cross reactivity with other proteins.

Background: In molecular biology, the CUT domain (also known as ONECUT) is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, which is often found downstream of the CUT domain. It is mapped to 18q21.31. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ONECUT2, identical to the related mouse sequence.

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Jacquemin, P., Lannoy, V. J., Rousseau, G. G., Lemaigre, F. P. OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6. J. Biol. Chem. 274: 2665-2671, 1999. 2. Plaisance, V., Abderrahmani, A., Perret-Menoud, V., Jacquemin, P., Lemaigre, F., Regazzi, R. MicroRNA-9 controls the expression of granuphilin/slp4 and the secretory response of insulin-producing cells. J. Biol. Chem. 281: 26932-26942, 2006.

Uniprot ID: O95948

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 54 kDa

Calculated Molecular Weight:

Gene ID: 9480

Protein Name: One cut domain family member 2

Gene Full Name: one cut homeobox 2

Synonyms: HNF 6 beta; HNF6B; OC 2; OC2; One cut domain family member 2; one cut homeobox 2; ONECUT2; Transcription factor ONECUT 2