Anti-NUDT18 Antibody Picoband®

SKU: A14058-2

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: NUDT18

Specificity:

Background: The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules. This protein contains a Nudix hydrolase domain and hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates.

Immunogen: E.coli-derived human NUDT18 recombinant protein (Position: M1-R291). Human NUDT18 shares 82.8% and 83.2% amino acid (aa) sequence identity with mouse and rat NUDT18, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Hartz, P. A. Personal Communication. Baltimore, Md. 5/13/2014. 2. Takagi, Y., Setoyama, D., Ito, R., Kamiya, H., Yamagata, Y., Sekiguchi, M. Human MTH3 (NUDT18) protein hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates: comparison with MTH1 and MTH2. J. Biol. Chem. 287: 21541-21549, 2012.

Uniprot ID: Q6ZVK8

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 36 kDa

Calculated Molecular Weight: 36 kDa

Gene ID: 79873

Protein Name: 8-oxo-dGDP phosphatase NUDT18

Gene Full Name: nudix hydrolase 18

Synonyms: MTH3; Nucleoside diphosphate-linked moiety X motif 18; EC:3.6.1.58; 8-oxo-dGDP phosphatase NUDT18; 7;8-dihydro-8-oxoguanine phosphatase