Anti-NAV3 Antibody Picoband®

SKU: A07567-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: NAV3

Specificity:

Background: This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined.

Immunogen: E.coli-derived human NAV3 recombinant protein (Position: K9-D1417). Human NAV3 shares 91.9% amino acid (aa) sequence identity with mouse NAV3.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Coy, J. F., Wiemann, S., Bechmann, I., Bachner, D., Nitsch, R., Kretz, O., Christiansen, H., Poustka, A. Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. Gene 290: 73-94, 2002. 2. Maes, T., Barcelo, A., Buesa, C. Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans. Genomics 80: 21-30, 2002. 3. Nagase, T., Ishikawa, K., Suyama, M., Kikuno, R., Hirosawa, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6: 63-70, 1999.

Uniprot ID: Q8IVL0

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 256 kDa

Calculated Molecular Weight: 256 kDa

Gene ID: 89795

Protein Name: Neuron navigator 3

Gene Full Name: neuron navigator 3

Synonyms: NAV3; KIAA0938; POMFIL1; STEERIN3; Neuron navigator 3; Pore membrane and/or filament-interacting-like protein 1; Steerin-3; Unc-53 homolog 3; unc53H3