Anti-MC5R Antibody Picoband®

SKU: A07019-3

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: WB

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat

Gene Name: MC5R

Specificity:

Background: Predicted to enable hormone binding activity and melanocortin receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to be active in cytoplasm and plasma membrane. Is expressed in skin. Orthologous to human MC5R (melanocortin 5 receptor).

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse MC5R. Mouse MC5R shares 95.5% amino acid (aa) sequence identity with both human and rat MC5R.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Chen, W., Kelly, M. A., Opitz-Araya, X., Thomas, R. E., Low, M. J., Cone, R. D. Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides. Cell 91: 789-798, 1997. 2. Chowdhary, B. P., Gustavsson, I., Wikberg, J. E. S., Chhajlani, V. Localization of the human melanocortin-5 receptor gene (MC5R) to chromosome band 18p11.2 by fluorescence in situ hybridization. Cytogenet. Cell Genet. 68: 79-81, 1995. 3. Gantz, I., Shimoto, Y., Konda, Y., Miwa, H., Dickinson, C. J., Yamada, T. Molecular cloning, expression, and characterization of a fifth melanocortin receptor. Biochem. Biophys. Res. Commun. 200: 1214-1220, 1994.

Uniprot ID: P41149

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 37 kDa

Calculated Molecular Weight: 37 kDa

Gene ID: 17203

Protein Name: Melanocortin receptor 5

Gene Full Name: melanocortin 5 receptor

Synonyms: Mc5r; Melanocortin receptor 5; MC5-R