Anti-LMO2 Antibody Picoband®

SKU: A03502-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IP,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunoprecipitation, 0.5-2 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: LMO2

Specificity:

Background: LIM domain only 2 (rhombotin-like 1), also known as LMO2, RBTNL1, RBTN2, RHOM2, LIM Domain Only Protein 2, TTG2, and T-Cell Translocation Protein 2, is a protein which in humans is encoded by the LMO2 gene. LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen: E.coli-derived human LMO2 recombinant protein (Position: A4-E150). Human LMO2 shares 100% amino acid (aa) sequence identity with mouse LMO2.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Berns, A. Good news for gene therapy. New Eng. J. Med. 350: 1679-1680, 2004. 2. Boehm, T., Foroni, L., Kaneko, Y., Perutz, M. F., Rabbitts, T. H. The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13. Proc. Nat. Acad. Sci. 88: 4367-4371, 1991. 3. Dave, U. P., Jenkins, N. A., Copeland, N. G. Gene therapy insertional mutagenesis insights. Science 303: 333 only, 2004.

Uniprot ID: P25791

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 22 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 4005

Protein Name: Rhombotin-2

Gene Full Name: LIM domain only 2

Synonyms: Cysteine rich protein TTG 2; LIM domain only protein 2; LMO 2; LMO2; RBTN2; RBTNL1; RHOM2; Rhombotin 2; T cell translocation protein 2; TTG2