Anti-KCNJ16 Antibody Picoband®

SKU: A10858-3

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Monkey

Applications: WB,Flow Cytometry

Application Details: Western blot, 0.25-0.5μg/ml, Human, Monkey
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human

Gene Name: KCNJ16

Specificity:

Background: Potassium inwardly-rectifying channel, subfamily J, member 16 (KCNJ16) is a human gene encoding the Kir5.1 protein. Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which tends to allow potassium to flow into rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may function in fluid and pH balance regulation. Alternatively spliced transcript variants have been found for this gene.

Immunogen: E.coli-derived human KCNJ16 recombinant protein (Position: M1-M418).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. D'Adamo, M. C., Shang, L., Imbrici, P., Brown, S. D. M., Pessia, M., Tucker, S. J. Genetic inactivation of Kcnj16 identifies Kir5.1 as an important determinant of neuronal PCO2/pH sensitivity. J. Biol. Chem. 286: 192-198, 2011. 2. Derst, C., Karschin, C., Wischmeyer, E., Hirsch, J. R., Preisig-Muller, R., Rajan, S., Engel, H., Grzeschik, K.-H., Daut, J., Karschin, A. Genetic and functional linkage of Kir5.1 and Kir2.1 channel subunits. FEBS Lett. 491: 305-311, 2001. 3. Liu, Y., McKenna, E., Figueroa, D. J., Blevins, R., Austin, C. P., Bennett, P. B., Swanson, R. The human inward rectifier K+ channel subunit Kir5.1 (KCNJ16) maps to chromosome 17q25 and is expressed in kidney and pancreas. Cytogenet. Cell Genet. 90: 60-63, 2000.

Uniprot ID: Q9NPI9

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 48 kDa

Calculated Molecular Weight:

Gene ID: 3773

Protein Name: Inward rectifier potassium channel 16

Gene Full Name: potassium inwardly rectifying channel subfamily J member 16

Synonyms: BIR9; KCNJ16; KIR5.1