Anti-JDP2 Antibody Picoband®

SKU: A04870-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: JDP2

Specificity:

Background: Jun dimerization protein 2 (JUNDM2) is a protein that in humans is encoded by the JDP2 gene. Mouse Jdp2 is an inhibitory subunit of the differentiation regulatory factor (DRF) complex. Jdp2 repressed retinoic acid-induced transcription of the Jun gene by recruiting a histone deacetylase-3 -containing complex to the differentiation response element (DRE) of the Jun promoter. Expression of JDP2 was reduced in several human cancers compared with matched normal tissues. Human JDP2 has antitumorigenic properties.

Immunogen: E.coli-derived human JDP2 recombinant protein (Position: E33-K163).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Gross, M. B. Personal Communication. Baltimore, Md. 7/23/2013. 2. Heinrich, R., Livne, E., Ben-Izhak, O., Aronheim, A. The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor gene. J. Biol. Chem. 279: 5708-5715, 2004. 3. Ji, H., Ehrlich, L. I. R., Seita, J., Murakami, P., Doi, A., Lindau, P., Lee, H., Aryee, M. J., Irizarry, R. A., Kim, K., Rossi, D. J., Inlay, M. A., Serwold, T., Karsunky, H., Ho, L., Daley, G. Q., Weissman, I. L., Feinberg, A. P. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature 467: 338-342, 2010.

Uniprot ID: Q8WYK2

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 19 kDa

Calculated Molecular Weight: 35883 MW

Gene ID: 122953

Protein Name: Jun dimerization protein 2

Gene Full Name: Jun dimerization protein 2

Synonyms: JDP2; Jun dimerization protein 2