Anti-IRF7 Antibody Picoband®

SKU: A00115-3

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: IRF7

Specificity:

Background: Interferon regulatory factor 7, also known as IRF7, is a member of the interferon regulatory factor family of transcription factors. This gene encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. It has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. The encoded protein plays an important role in the innate immune response against DNA and RNA viruses.

Immunogen: E.coli-derived human IRF7 recombinant protein (Position: Y27-A503).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Au, W.-C., Moore, P. A., LaFleur, D. W., Tombal, B., Pitha, P. M. Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes. J. Biol. Chem. 273: 29210-29217, 1998. 2. Au, W.-C., Yeow, W.-S., Pitha, P. M. Analysis of functional domain of interferon regulatory factor 7 and its association with IRF-3. Virology 280: 273-282, 2001. 3. Chen, H.-W., King, K., Tu, J., Sanchez, M., Luster, A. D., Shresta, S. The roles of IRF-3 and IRF-7 in innate antiviral immunity against Dengue virus. J. Immun. 191: 4194-4201, 2013.

Uniprot ID: Q92985

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 70 kDa

Calculated Molecular Weight: 21298 MW

Gene ID: 3665

Protein Name: Interferon regulatory factor 7

Gene Full Name: interferon regulatory factor 7

Synonyms: IRF 7; IRF 7H; IRF7; IRF7A