Anti-IFN Gamma/Ifng Antibody Picoband®

SKU: A00393-4

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Mouse

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, recombinant protein
ELISA, 0.1-0.5 μg/ml, -

Gene Name: Ifng

Specificity:

Background: This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mice deficient in this gene have increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.

Immunogen: E.coli-derived mouse IFN Gamma/Ifng recombinant protein (Position: H23-C155). Mouse Ifng shares 40.3% and 86.5% amino acid (aa) sequence identity with human and rat Ifng, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. An, P., Vlahov, D., Margolick, J. B., Phair, J., O'Brien, T. R., Lautenberger, J., O'Brien, S. J., Winkler, C. A. A tumor necrosis factor-alpha-inducible promoter variant of interferon-gamma accelerates CD4-positive T cell depletion in human immunodeficiency virus-1-infected individuals. J. Infect. Dis. 188: 228-231, 2003. 2. Arbore, G., West, E. E., Spolski, R., Robertson, A. A. B., Klos, A., Rheinheimer, C., Dutow, P., Woodruff, T. M., Yu, Z. X., O'Neill, L. A., Coll, R. C., Sher, A., and 10 others. T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells. Science 352: aad1210, 2016. Note: Electronic Article. 3. Awad, M., Pravica, V., Perrey, C., El Gamel, A., Yonan, N., Sinnott, P. J., Hutchinson, I. V. CA repeat allele polymorphism in the first intron of the human interferon-gamma gene is associated with lung allograft fibrosis. Hum. Immun. 60: 343-346, 1999.

Uniprot ID: P01580

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 78 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 15978

Protein Name: Interferon gamma

Gene Full Name: interferon gamma

Synonyms: IFG; IFI; IFN gamma; IFN γ; IFNG; IFN-gamma; IFN-γ