Anti-GLUT10/SLC2A10 Antibody Picoband®

SKU: A06461-2

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5μg/ml, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: SLC2A10

Specificity: No cross reactivity with other proteins.

Background: Solute carrier family 2, facilitated glucose transporter member 10 is a protein that in humans is encoded by the SLC2A10 gene. It is mapped to 20q13.12. This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.

Immunogen: E.coli-derived human GLUT10/SLC2A10 recombinant protein (Position: A32-Q511).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Faiyaz-Ul-Haque, M., Zaidi, S. H. E., Wahab, A. A., Eltohami, A., Al-Mureikhi, M. S., Al-Thani, G., Peltekova, V. D., Tsui, L.-C., Teebi, A. S. Identification of a pSer81Arg encoding mutation in SLC2A10 gene of arterial tortuosity syndrome patients from 10 Qatari families. (Letter) Clin. Genet. 74: 189-193, 2008. 2. Lee, Y.-C., Huang, H.-Y., Chang, C.-J., Cheng, C.-H., Chen, Y.-T. Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome. Hum. Molec. Genet. 19: 3721-3733, 2010. 3. McVie-Wylie, A. J., Lamson, D. R., Chen, Y. T. Molecular cloning of a novel member of the GLUT family of transporters, SLC2A10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility. Genomics 72: 113-117, 2001.

Uniprot ID: O95528

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 67 kDa

Calculated Molecular Weight:

Gene ID: 81031

Protein Name: Solute carrier family 2, facilitated glucose transporter member 10

Gene Full Name: solute carrier family 2 member 10

Synonyms: solute carrier family 2 member 10; ATORS; ATS; GLUT10; SLC2A10