Anti-GJA4 Antibody Picoband®

SKU: A05569-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,WB,IHC

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: GJA4

Specificity:

Background: Gap junction alpha-4 protein, also known as Connexin-37 or Cx37, is a protein that in humans is encoded by the GJA4 gene. This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

Immunogen: E.coli-derived human GJA4 recombinant protein (Position: H95-R148). Human GJA4 shares 90.7% and 92.6% amino acid (aa) sequence identity with mouse and rat GJA4, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Boerma, M., Forsberg, L., Van Zeijl, L., Morgenstern, R., De Faire, U., Lemne, C., Erlinge, D., Thulin, T., Hong, Y., Cotgreave, I. A. A genetic polymorphism in connexin 37 as a prognostic marker for atherosclerotic plaque development. J. Intern. Med. 246: 211-218, 1999 2. Haefliger, J.-A., Bruzzone, R., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Paul, D. L. Four novel members of the connexin family of gap junction proteins: molecular cloning, expression, and chromosome mapping. J. Biol. Chem. 267: 2057-2064, 1992. 3. Peters, R. J. G., Boekholdt, S. M. Gene polymorphisms and the risk of myocardial infarction--an emerging relation. (Editorial) New Eng. J. Med. 347: 1963-1965, 2002.

Uniprot ID: P35212

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 40 kDa

Calculated Molecular Weight: 37 kDa

Gene ID: 2701

Protein Name: Gap junction alpha-4 protein

Gene Full Name: gap junction protein alpha 4

Synonyms: GJA4; Gap junction alpha-4 protein; Connexin-37; Cx37