Anti-Cytochrome P450 3A4 CYP3A4 Monoclonal Antibody

SKU: M00339

Size: 100 μl

Storage: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Form: Liquid

Reactivity: Human

Applications: WB,IHC,IP

Application Details: WB 1:1000-1:5000
IHC 1:50-1:200
IP 1:50

Gene Name: CYP3A4

Specificity:

Background:

Immunogen: A synthesized peptide derived from human Cytochrome P450 3A4 Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. The enzyme also hydroxylates etoposide.

Clonality: Monoclonal

Contents: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Affinity-chromatography

Reconstitution:

Reference:

Uniprot ID: P08684

Host: Rabbit

Concentration: 0.5mg/ml

Conjugate:

Cross Reactivity:

Isotype: Rabbit IgG

Phospho_site:

Clone Number: Clone: ACDE-3

Observed Molecular Weight: 32 kDa

Calculated Molecular Weight: 44702 MW

Gene ID: 1576

Protein Name: Cytochrome P450 3A4

Gene Full Name: cytochrome P450 family 3 subfamily A member 4

Synonyms: Albendazole monooxygenase; Albendazole sulfoxidase; CP33; CP34; CYP3A; CYP3A11; CYP3A3; CYP3A4; CYPIIIA3; CYPIIIA4; Cytochrome P450 3A3; Cytochrome P450 3A4; Cytochrome P450 HLp; Cytochrome P450 NF 25; Cytochrome P450 PCN1; HLP; NF 25; Nifedipine oxidase; P450C3; P450PCN1; Quinine 3 monooxygenase