Anti-CPAMD8 Antibody Picoband®

SKU: A12898

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Monkey

Applications: ELISA,IHC,WB

Application Details: Western blot, 0.1-0.5μg/ml, Human, Monkey
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: CPAMD8

Specificity: No cross reactivity with other proteins.

Background: CPAMD8 belongs to the complement component-3 (C3; 120700)/alpha-2-macroglobulin (A2M; 103950) family of proteins, which are involved in innate immunity and damage control. The encoded protein is membrane-associated and proteolytically processed to generate two chains. Mutations in this gene cause a form of anterior segment dysgenesis, a developmental disorder of the eye. By genomic sequence analysis, the CPAMD8 gene is mapped to chromosome 19p13.3-p13.2.

Immunogen: E.coli-derived human CPAMD8 recombinant protein (Position: R58-D234).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Cheong, S.-S., Hentschel, L., Davidson, A. E., Gerrelli, D., Davie, R., Rizzo, R., Pontikos, N., Plagnol, V., Moore, A. T., Sowden, J. C., Michaelides, M., Snead, M., Tuft, S. J., Hardcastle, A. J. Mutations in CPAMD8 cause a unique form of autosomal-recessive anterior segment dysgenesis. Am. J. Hum. Genet. 99: 1338-1352, 2016. 2. Li, Z.-F., Wu, X., Engvall, E. Identification and characterization of CPAMD8, a novel member of the complement 3/alpha-2-macroglobulin family with a C-terminal Kazal domain. Genomics 83: 1083-1093, 2004.

Uniprot ID: Q8IZJ3

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 207 kDa

Calculated Molecular Weight:

Gene ID: 27151

Protein Name: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8

Gene Full Name: C3 and PZP like alpha-2-macroglobulin domain containing 8

Synonyms: CPAMD8; KIAA1283; VIP; ASGD8; K-CAP