Anti-Contactin 1/CNTN1 Antibody Picoband®

SKU: A04538-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ICC,IF,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: CNTN1

Specificity:

Background: Contactin 1, also known as CNTN1, is a protein which in humans is encoded by the CNTN1 gene. The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human Contactin 1/CNTN1 recombinant protein (Position: K225-H979).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Berglund, E. O., Murai, K. K., Fredette, B., Sekerkova, G., Marturano, B., Weber, L., Mugnaini, E., Ranscht, B. Ataxia and abnormal cerebellar microorganization in mice with ablated contactin gene expression. Neuron 24: 739-750, 1999. 2. Berglund, E. O., Ranscht, B. Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12. Genomics 21: 571-582, 1994. 3. Boyle, M. E. T., Berglund, E. O., Murai, K. K., Weber, L., Peles, E., Ranscht, B. Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve. Neuron 30: 385-397, 2001.

Uniprot ID: Q12860

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 135 kDa

Calculated Molecular Weight:

Gene ID: 1272

Protein Name: Contactin-1

Gene Full Name: contactin 1

Synonyms: CNTN1; contactin 1; F3; Glycoprotein gp135; GP135; Neural cell surface protein F3