Anti-CDw75/ST6GAL1 Antibody Picoband®

SKU: A03156-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ST6GAL1

Specificity:

Background: Beta-galactoside alpha-2,6-sialyltransferase 1 is an enzyme that in humans is encoded by the ST6GAL1 gene. This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternative splicing results in multiple transcript variants.

Immunogen: E.coli-derived human CDw75/ST6GAL1 recombinant protein (Position: M1-C406).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Grundmann, U., Nerlich, C., Rein, T., Zettlmeissl, G. Complete cDNA sequence encoding human beta-galactoside alpha-2,6-sialyltransferase. Nucleic Acids Res. 18: 667 only, 1990. 2. Kitagawa, H., Paulson, J. C. Differential expression of five sialyltransferase genes in human tissues. J. Biol. Chem. 269: 17872-17878, 1994. 3. Nicholls, J. M., Chan, M. C. W., Chan, W. Y., Wong, H. K., Cheung, C. Y., Kwong, D. L. W., Wong, M. P., Chui, W. H., Poon, L. L. M., Tsao, S. W., Guan, Y., Peiris, J. S. M. Tropism of avian influenza A (H5N1) in the upper and lower respiratory tract. Nature Med. 13: 147-149, 2007.

Uniprot ID: P15907

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 47 kDa

Calculated Molecular Weight: 65411 MW

Gene ID: 6480

Protein Name: Beta-galactoside alpha-2,6-sialyltransferase 1

Gene Full Name: ST6 beta-galactoside alpha-2,6-sialyltransferase 1

Synonyms: Alpha 2; 6 ST 1; B cell antigen CD75; CD75; Sialyltransferase 1; SIAT1; ST6Gal I; ST6GAL1; ST6GalI; ST6N