Anti-CD98/Slc3a2 Antibody Picoband®

SKU: A01794-3

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml/ml, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/ml/1x10^6 cells, Mouse
ELISA, 0.1-0.5 μg/ml/ml, Mouse

Gene Name: Slc3a2

Specificity:

Background: 4F2 cell-surface antigen heavy chain is a protein that in humans is encoded by the SLC3A2 (solute carrier family 3 member 2) gene. Predicted to enable amino acid transmembrane transporter activity and double-stranded RNA binding activity. Predicted to be involved in carboxylic acid transport and viral entry into host cell. Predicted to act upstream of or within response to exogenous dsRNA. Located in apical pole of neuron. Is active in synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and spinal cord. Orthologous to human SLC3A2 (solute carrier family 3 member 2).

Immunogen: E.coli-derived mouse CD98/Slc3a2 recombinant protein (Position: K35-Q497).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Cantor, J., Slepak, M., Ege, N., Chang, J. T., Ginsberg, M. H. Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity. J. Immun. 187: 851-860, 2011. 2. Courseaux, A., Grosgeorge, J., Gaudray, P., Pannett, A. A. J., Forbes, S. A., Williamson, C., Bassett, D., Thakker, R. V., Teh, B. T., Farnebo, F., Shepherd, J., Skogseid, B., Larsson, C., Giraud, S., Zhang, C. X., Salandre, J., Calender, A. Definition of the minimal MEN1 candidate area based on a 5-Mb integrated map of proximal 11q13. Genomics 37: 354-365, 1996. 3. Feral, C. C., Nishiya, N., Fenczik, C. A., Stuhlmann, H., Slepak, M., Ginsberg, M. H. CD98hc (SLC3A2) mediates integrin signaling. Proc. Nat. Acad. Sci. 102: 355-360, 2005.

Uniprot ID: P10852

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 80-90 kDa

Calculated Molecular Weight:

Gene ID: 17254

Protein Name: Amino acid transporter heavy chain SLC3A2

Gene Full Name: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

Synonyms: 4F2; 4F2 heavy chain antigen; 4F2HC; 4T2HC; CD98; CD98/SLC3A2; CD98HC; MDU1; NACAE; SLC3A2