Anti-BCHE Antibody Picoband®

SKU: A00258-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: BCHE

Specificity:

Background: This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine.

Immunogen: E.coli-derived human BCHE recombinant protein (Position: E29-L602). Human BCHE shares 80.8% amino acid (aa) sequence identity with mouse BCHE.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Alberti, J., Martinet, A., Sentellas, S., Salva, M. Identification of the human enzymes responsible for the enzymatic hydrolysis of aclidinium bromide. Drug Metab. Dispos. 38: 1202-1210, 2010. 2. Allderdice, P. W., Gardner, H. A. R., Galutira, D., Lockridge, O., LaDu, B. N., McAlpine, P. J. The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26. Genomics 11: 452-454, 1991. 3. Altland, K., Goedde, H. W. Heterogeneity in the silent gene phenotype of pseudocholinesterase of human serum. Biochem. Genet. 4: 321-338, 1970.

Uniprot ID: P06276

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 85-90 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 590

Protein Name: Cholinesterase

Gene Full Name: butyrylcholinesterase

Synonyms: Acylcholine acylhydrolase; BCHE; Butyrylcholine esterase; butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase; E1; Pseudocholinesterase; BCHED; CHE2