Anti-ATE1 Antibody Picoband®

SKU: A07459-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ATE1

Specificity:

Background: This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in multiple transcript variants.

Immunogen: E.coli-derived human ATE1 recombinant protein (Position: R56-A459).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Hu, R.-G., Sheng, J., Qi, X., Xu, Z., Takahashi, T. T., Varshavsky, A. The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators. Nature 437: 981-986, 2005. 2. Kaji, H., Novelli, G. D., Kaji, A. A soluble amino acid-incorporating system from rat liver. Biochim. Biophys. Acta 76: 474-477, 1963. 3. Karakozova, M., Kozak, M., Wong, C. C. L., Bailey, A. O., Yates, J. R, III, Mogilner, A., Zebroski, H., Kashina, A. Arginylation of beta-actin regulates actin cytoskeleton and cell motility. Science 313: 192-196, 2006.

Uniprot ID: O95260

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 59 kDa

Calculated Molecular Weight: 51200 MW

Gene ID: 11101

Protein Name: Arginyl-tRNA--protein transferase 1

Gene Full Name: arginyltransferase 1

Synonyms: arginyltransferase 1; ATE1; R transferase 1