Anti-ARS2/SRRT Antibody Picoband®

SKU: A05444-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF,IP,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Immunoprecipitation, 0.5-2 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SRRT

Specificity:

Background: Serrate RNA effector molecule homolog (SRRT) also known as arsenite-resistance protein 2 (ARS2) is a protein that in humans is encoded by the SRRT gene. Enables mRNA cap binding complex binding activity and protein-macromolecule adaptor activity. Involved in primary miRNA processing. Located in nucleoplasm. Part of ribonucleoprotein complex.

Immunogen: E.coli-derived human ARS2/SRRT recombinant protein (Position: H125-Q793).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Andreu-Agullo, C., Maurin, T., Thompson, C. B., Lai. E. C. Ars2 maintains neural stem-cell identity through transcriptional activation of Sox2. Nature 481: 195-198, 2011. 2. Gruber, J. J., Zatechka, D. S., Sabin, L. R., Yong, J., Lum, J. J., Kong, M., Zong, W.-X., Zhang, Z., Lau, C.-K., Rawlings, J., Cherry, S., Ihle, J. N., Dreyfuss, G., Thompson, C. B. Ars2 links nuclear cap-binding complex to RNA interference and cell proliferation. Cell 138: 328-339, 2009. 3. Kiriyama, M., Kobayashi, Y., Saito, M., Ishikawa, F., Yonehara, S. Interaction of FLASH with arsenite resistance protein 2 is involved in cell cycle progression at S phase. Molec. Cell. Biol. 29: 4729-4741, 2009.

Uniprot ID: Q9BXP5

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 101 kDa

Calculated Molecular Weight: 101 kDa

Gene ID: 51593

Protein Name: Serrate RNA effector molecule homolog

Gene Full Name: serrate, RNA effector molecule

Synonyms: SRRT; ARS2; ASR2; Serrate RNA effector molecule homolog; Arsenite-resistance protein 2