Anti-Apolipoprotein L1/APOL1 Antibody Picoband®

SKU: A01841-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: ELISA,IHC,WB

Application Details: Western blot, 0.25-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: APOL1

Specificity: No cross reactivity with other proteins.

Background: Apolipoprotein L1 is a protein that in humans is encoded by the APOL1 gene. It is mapped to 22q12.3. This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human Apolipoprotein L1/APOL1 recombinant protein (Position: M228-L398).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Page NM, Butlin DJ, Lomthaisong K, Lowry PJ (May 2001). The human apolipoprotein L gene cluster: identification, classification, and sites of distribution. Genomics. 74 (1): 71–8. 2. Pérez-Morga D, Vanhollebeke B, Paturiaux-Hanocq F, Nolan DP, Lins L, Homblé F, Vanhamme L, Tebabi P, Pays A, Poelvoorde P, Jacquet A, Brasseur R, Pays E (July 2005). Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes. Science. 309 (5733): 469–72. 3. Monajemi H, Fontijn RD, Pannekoek H, Horrevoets AJ (April 2002). The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue. Genomics. 79 (4): 539–46.

Uniprot ID: O14791

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 37 kDa

Calculated Molecular Weight:

Gene ID: 8542

Protein Name: Apolipoprotein L1

Gene Full Name: apolipoprotein L1

Synonyms: APO L; APOL; APOL I; APOL1; Apolipoprotein L; Apolipoprotein L I; apolipoprotein L 1; Apolipoprotein L1