ANK3 Polyclonal Antibody

SKU: E-AB-13058

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ANK3

Target Synonym: ANK-3;ANK3;ANK3;ankyrin 3 (G);Ankyrin 3;node of Ranvier (ankyrin G);Ankyrin 3;node of Ranvier;Ankyrin G119;Ankyrin-3;Ankyrin-G;brain specific ankyrin G;CHANK3;FLJ45464;OTTHUMP00000217458;OTTHUMP00000217575;RP11 369L1.1

Research Areas: Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q12955

Accession:

Background: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.9 mg/mL

Immunogen: Synthetic peptide of human ANK3

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:25-1:100

Calculated MW:

ObservedMW: