AMPK beta 2 Rabbit Polyclonal Antibody

SKU: BT-AP01684

Size:100μL

Background:AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase. This is a regulatory subunit| may be a positive regulator of AMPK activity. It may also serve as an adapter molecule for the catalytic alpha-subunit.|PTM:Phosphorylated when associated with the catalytic subunit.|Belongs to the 5'-AMP-activated protein kinase beta subunit family.|subunit:Heterotrimer of an alpha catalytic subunit| a beta and a gamma non-catalytic regulatory subunits.|

Research_area:Cancer; Cardiovascular; Metabolism; Signal transduction

Target_protein:PRKAB2

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:AMPKbeta 2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):29920

UniProt accession:Human: O43741; Mouse: Q6PAM0; Rat: Q9QZH4

Synonyms:AMPKβ2; 5'-AMP-activated protein kinase subunit beta-2; AMPK subunit beta-2

GeneID:Human: 5565; Mouse: 108097; Rat: 64562