AIMP1/EMAP II Monoclonal Antibody

SKU: AN200183P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:AIMP1

Target Synonym:HLD;AIMP;EMAP;SCYE;AIMP1;EMAP2;EMAPII;HLD3;SCYE1;p43;AIMP 1;AIMP1/p43;Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1;ARS interacting multifunctional protein 1;EMAP 2;EMAP-2;EMAP-II;Endothelial monocyte activating polypeptide;Endothelial monocyte activating polypeptide 2;Endothelial monocyte-activating polypeptide 2;Endothelial monocyte-activating polypeptide II;formerly;member 1;member 1 (endothelial monocyte-activating);Multisynthase complex auxiliary component p43;Multisynthetase complex auxiliary component p43;OTTHUMP00000219673;Scye 1;Small inducible cytokine subfamily E;Small inducible cytokine subfamily E member 1

Research Areas:Cell Biology;Cardiovascular;Immunology;Tags & Cell Markers;Epigenetics and Nuclear Signaling;Cancer

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:IHC-P

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:6A4

UNIProt ID:Q12904

Accession:

Background:The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.

Concentration:1 mg/mL

Immunogen:Recombinant Human AIMP1/EMAP II Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:20-1:80

Calculated MW:

ObservedMW: