AHR Antibody, FITC conjugated - Cat. #: CSB-PA001481LC01HU

SKU: CSB-PA001481LC01HU

Size :50ug

Clone Number:

Aliases:Ah receptor antibody; AhR antibody; AHR_HUMAN antibody; Aromatic hydrocarbon receptor antibody; Aryl hydrocarbon receptor antibody; Aryl hydrocarbon receptor precursor antibody; bHLHe76 antibody; Class E basic helix loop helix protein 76 antibody; Class E basic helix-loop-helix protein 76 antibody; HGNC:348 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P35869

Immunogen:Recombinant Human Aryl hydrocarbon receptor protein (126-353AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:AHR

Research Areas:Epigenetics and Nuclear Signaling