AF/LE Purified Anti-Human CD85j Antibody[GHI/75]

SKU: AN002890

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD85j

Target Synonym:LILRB;ILT;LIR;MIR;LILRB1;CD85J;ILT-2;ILT2;LIR-1;LIR1;MIR-7;MIR7;PIR-B;PIRB; ILT2; LILRB1;CD85;CD85 antigen;CD85 antigen like family member J;CD85 antigen-like family member J;CD85j antigen;Ig like transcript 2;ILT 2;immunoglobulin like transcript 2;Immunoglobulin-like transcript 2;leukocyte Ig like receptor 1;leukocyte immunoglobulin like receptor;Leukocyte immunoglobulin like receptor 1;leukocyte immunoglobulin like receptor subfamily B member 1;Leukocyte immunoglobulin like receptor subfamily B member 1 precursor;leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform;leukocyte immunoglobulin-like receptor;Leukocyte immunoglobulin-like receptor 1;Leukocyte immunoglobulin-like receptor subfamily B member 1;leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform;LIR 1;LIRB1;member 1;MIR 7;Monocyte/macrophage immunoglobulin like receptor 7;Monocyte/macrophage immunoglobulin-like receptor 7;PIR B;subfamily B;subfamily B (with TM and ITIM domains)

Research Areas:Immunology

Conjugation:None (AF/LE)

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG2b, κ

Clonality:Monoclonal

Clone NO.:GHI/75

UNIProt ID:Q8NHL6

Background:This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD85j protein

Buffer:Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:10859