AF/LE Purified Anti-Human CD62L Antibody[DREG56]

SKU: GBS-F10510

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD62L

Target Synonym:Leukocyte adhesion molecule;Leukocyte surface antigen Leu;Leukocyte-endothelial cell adhesion molecule;LECAM;LAM;LEU;SELL;CD62L;LAM1;LECAM1;LEU8;LNHR;LSEL;LYAM1;PLNHR;TQ1;CD62 antigen-like family member L;CD62antigen-likefamilymemberL;gp90-MEL;LAM-1;Leu-8;Leukocyte adhesion molecule 1;Leukocyte surface antigen Leu-8;Leukocyte-endothelial cell adhesion molecule 1;L-selectin;Ly22;Ly-22;Lyam-1;Lymph node homing receptor;Lymphnodehomingreceptor;6&apos- sulfated Lewis X-X; LECAM-1; LAM-1

Research Areas:Cardiovascular;Immunology;Stem Cells

Conjugation:None (AF/LE)

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG1, κ

Clonality:Monoclonal

Clone NO.:DREG56

UNIProt ID:P14151

Background:CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD62L protein

Buffer:Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:6402