ADRM1 Polyclonal Antibody

SKU: E-AB-52740

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:ADRM1

Target Synonym:110 kDa cell membrane glycoprotein;adhesion regulating molecule 1;Adhesion-regulating molecule 1;ADRM 1;Adrm1;ADRM1;ARM 1;ARM-1;ARM1;Gp110;hRpn13;M(r) 110;000 surface antigen;Proteasomal ubiquitin receptor ADRM1;proteasome regulatory particle non ATPase 13;Proteasome regulatory particle non-ATPase 13;Regulatory particle non ATPase 13;Rpn13;Rpn13 homolog

Research Areas:Cancer;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q16186

Accession:

Background:The 26S proteasome is a key component of the ubiquitin-proteasome system,a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme,UCH37,and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.

Concentration:0.54 mg/mL

Immunogen:Fusion protein of human ADRM1

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:40-1:200

Calculated MW:

ObservedMW: