ADAM15 Antibody, Biotin conjugated - Cat. #: CSB-PA01915D0Rb

SKU: CSB-PA01915D0Rb

Size :50ug

Clone Number:

Aliases:A disintegrin and metalloproteinase domain 15 (metargidin) antibody; A disintegrin and metalloproteinase domain 15 antibody; ADA15_HUMAN antibody; ADAM 15 antibody; ADAM metallopeptidase domain 15 antibody; Adam15 antibody; and cysteine-rich protein 15 antibody; Disintegrin and metalloproteinase domain-containing protein 15 antibody; disintegrin-like antibody; EC 3.4.24. antibody; MDC 15 antibody; MDC-15 antibody; MDC15 antibody; Metalloprotease RGD disintegrin protein antibody; Metalloproteinase like disintegrin like and cysteine rich protein 15 antibody; Metalloproteinase-like antibody; Metargidin antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13444

Immunogen:Recombinant Human Disintegrin and metalloproteinase domain-containing protein 15 protein (207-452AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ADAM15

Research Areas:Cancer; Cell biology; Signal transduction