Size :100ul
Clone Number:
Aliases:AAK 1 antibody; Aak1 antibody; AAK1_HUMAN antibody; Adaptor associated kinase 1 antibody; Adaptor-associated kinase 1 antibody; AP2 associated kinase 1 antibody; AP2 associated protein kinase 1 antibody; AP2-associated protein kinase 1 antibody; DKFZp686F03202 antibody; DKFZp686K16132 antibody; FLJ23712 antibody; FLJ25931 antibody; FLJ31060 antibody; FLJ42882 antibody; FLJ45252 antibody; KIAA1048 antibody; MGC138170 antibody; MGC164568 antibody; MGC164570 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q2M2I8
Immunogen:Fusion protein corresponding to N terminal 236 amino acids of Human Adaptor-associated protein kinase 1
Raised in:Rabbit
Species Reactivity:Human, Mouse, Rat
Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:200
Background:
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Affinity purification
Conjugate:Non-conjugated
Buffer:Supplied at 1.1mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:AAK1
Research Areas:Others