Size :50ul
Clone Number:
Aliases:AADACL2Arylacetamide deacetylase-like 2 antibody; EC 3.1.1.- antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q6P093
Immunogen:Fusion protein of Human AADACL2
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100
Background:AADAC is a 45 kDa membrane-associated hydrolase highly expressed in the human liver that has been implicated in the hydrolysis of arylacetamide xenobiotics including flutamide and phenacetin.556–560AADAC is highly homologous to several related lipases, AADACL1, 2, and 4, the latter two of which remain completely unannotated. Overexpression of AADAC in a rat hepatoma cell line produces changes in cellular TG levels, apoplipoprotein B secretion, and fatty acid oxidation, but the mechanism for these effects remains unclear.561 Candidate endogenous substrates, selective inhibitors, or knockout mice have not, to our knowledge, been described for AADAC or the related enzymes AADACL2 and AADACL4.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:AADACL2
Research Areas:Cancer;Metabolism;Signal transduction