4.1R (phospho Tyr660) rabbit pAb

SKU: ES5122

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Mouse

Dilution:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human EPB41 around the phosphorylation site of Tyr660/418. AA range:626-675

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):60kD

Human_gene_id:2035

Human_swiss_prot_no:P11171

Subcellular_location:Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Nucleus .

Other_name:EPB41; E41P; Protein 4.1; P4.1; 4.1R; Band 4.1; EPB4.1

Background:The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Oct 2009],