LATS2 Antibody - Cat. #: CSB-PA697830

SKU: CSB-PA697830

Size :50ul

Clone Number:

Aliases:FLJ13161 antibody; Kinase phosphorylated during mitosis protein antibody; KPM antibody; Large tumor suppressor homolog 2 antibody; Large tumor suppressor homolog 2 Drosophila antibody; Large tumor suppressor kinase 2 antibody; LATS large tumor suppressor Drosophila homolog 2 antibody; LATS large tumor suppressor homolog 2 antibody; Lats2 antibody; LATS2_HUMAN antibody; Serine/threonine kinase kpm antibody; Serine/threonine protein kinase kpm antibody; Serine/threonine-protein kinase kpm antibody; Serine/threonine-protein kinase LATS2 antibody; Warts like kinase antibody; Warts-like kinase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NRM7

Immunogen:Synthetic peptide of Human LATS2

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100

Background:This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LATS2

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Signal transduction