Irf8 Antibody, HRP conjugated - Cat. #: CSB-PA011823HB01MO

SKU: CSB-PA011823HB01MO

Size :50ug

Clone Number:

Aliases:Irf8 antibody; Icsbp antibody; Icsbp1 antibody; Interferon regulatory factor 8 antibody; IRF-8 antibody; Interferon consensus sequence-binding protein antibody; ICSBP antibody

Product Type:Polyclonal Antibody

Immunogen Species:Mus musculus (Mouse)

UniProt ID:P23611

Immunogen:Recombinant Mouse Interferon regulatory factor 8 protein (1-424AA)

Raised in:Rabbit

Species Reactivity:Mouse

Tested Applications:ELISA

Background:Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\'-TGAnTCA/GAAA-3\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Irf8

Research Areas:Epigenetics and Nuclear Signaling; Immunology